• Users Online: 26
  • Print this page
  • Email this page
Year : 2019  |  Volume : 9  |  Issue : 2  |  Page : 95-99

Role of Vitamin D deficiency among patients with acute coronary syndrome

Department of Cardiology, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Correspondence Address:
Dr. Ahmed Shawky Shereef
Department of Cardiology, Faculty of Medicine, Zagazig University, Zagazig
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JICC.JICC_22_19

Rights and Permissions

Background: Previous studies demonstrated that low Vitamin D levels are associated with hypertension, obesity, dyslipidemia, and diabetes mellitus, reflecting an increased cardiovascular (CV) risk burden. However, high levels can be associated with increased total and CV mortality. Hence, we aimed to evaluate the prevalence of Vitamin D deficiency and if it has a role in the occurrence of acute coronary syndrome (ACS). Patients and Methods: This study was carried out on 71 patients presented with ACS, undergoing coronary angiography at the cardiology department, Zagazig university hospitals. Exclusion Criteria: Disorders causing Vitamin D deficiency. Methods: All our patients were subjected to (1) careful history-taking; (2) thorough clinical examination; (3) resting electrocardiogram; (4) routine laboratory investigations beside thyroid, parathyroid hormone, Mg, Ph, and Vitamin D levels; (5) echocardiography; and (6) coronary angiography. Results: In the present study, receiver-operating characteristic curve analysis shows that the serum Vitamin D has a cutoff value ≤41.5 nm/L to predict ACS with 94.4% sensitivity and 83% specificity, a cutoff value ≤41.5 nm/L to predict unstable angina with 97.3% sensitivity and 83% specificity a cutoff value ≤52.625 nm/L to predict ST-elevation myocardial infarction (STEMI) with 100% sensitivity and 76.6% specificity, and a cutoff value ≤41 nm/L to predict non-STEMI with 100% sensitivity and 83% specificity. Conclusion and Recommendations: Vitamin D deficiency and insufficiency are common in patients with ACS. Further, larger multicenter studies are needed to assess Vitamin D level in ACS patients and to investigate its relationship with long term prognosis.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded184    
    Comments [Add]    

Recommend this journal