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Year : 2019  |  Volume : 9  |  Issue : 2  |  Page : 108-110

Kounis syndrome: Allergic myocardial infarction!!

Department of Cardiology, Fortis Hospital, Bengaluru, Karnataka, India

Correspondence Address:
Dr. Deepak Kadeli
Department of Cardiology, Fortis Hospital, Cunningham Road, Bengaluru - 560 052, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JICC.JICC_16_19

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Anaphylaxis is a type 1 hypersensitivity reaction where the body reacts to an allergen within minutes. Free antigens cross-link the IgE on mast cells and basophils, which causes a release of vasoactive biomolecules which cause systemic vasospasm. A wide range of causes include insect bites and stings, foods, and medications. It can manifest with a constellation of symptoms, but common manifestations include urticaria, shortness of breath, vomiting, lightheadedness, and low blood pressure. Some unusual presentations include gastrointestinal symptoms such as loose stools and abdominal pain, but in rare cases, they may present as myocardial infarction. We present a case of a 49-year-old female who presented with effort angina and developed severe anaphylactic reaction to the dye used in angiogram, precipitating an inferior wall myocardial infarction.

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