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Year : 2019  |  Volume : 9  |  Issue : 4  |  Page : 186-192

A clinical study of prognostic significance of left atrial volume index in patients with acute coronary syndrome

Department of Cardiology, Osmania Medical College/General Hospital, Hyderabad, Telangana, India

Correspondence Address:
Dr. Praveen Nagula
Osmania Medical College/General Hospital, Afzal Gunj, Hyderabad - 500 012, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JICC.JICC_39_19

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Background: The aim of the study is to determine the relationship of left atrial volume index (LAVI) with the clinical presentation, comorbidities, and adverse events in acute coronary syndrome (ACS) patients at admission and during their follow-up. Methods: A total of 160 ACS patients enrolled have been divided into Group A (LAVI > 34 ml/m2) and Group B ( LAVI ≤ 34 ml/m2). The symptoms and the LAVI have been assessed at 1, 6, and 12 months of follow-up. The primary end point was cardiovascular (CV) mortality. The secondary end point is the occurrence of major adverse CV events, i.e., repeat hospitalization postdischarge for heart failure, reinfarction, atrial fibrillation, or ischemic stroke. Results: Overall, the median age at presentation was 55 years. There was no sex predilection for increased LAVI or an association with conventional risk factors. The echocardiographic E wave velocity divided by propagation velocity had a positive correlation with the LAVI (r = 0.321, P = 0.0036). The relative risk of morbidity with an increased LAVI was 2.74. The hazard ratio for adverse events in patients with increased LAVI was 2.81. The total number of deaths was 21 (16 and 5 in Group A and B). The LAVI was found to be the independent predictor of mortality than left ventricular ejection fraction on multivariate regression analysis. The receiver operating characteristic curve analysis had an area under the curve of 0.801 for increased LAVI. Conclusion: The LAVI is an independent predictor of adverse events and mortality during the initial hospital stay and at follow-up in ACS patients.

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