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ORIGINAL ARTICLE
Year : 2019  |  Volume : 9  |  Issue : 2  |  Page : 78-82

Assessment of left ventricular filling pressure and its correlation with severity of chronic kidney disease


1 Senior Resident, Department of Cardiology, Mahatma Gandhi Medical College and Research Institute, SBV University, Puducherry, India
2 Associate Professor, Department of Cardiology, Mahatma Gandhi Medical College and Research Institute, SBV University, Puducherry, India
3 Associate Professor, Department of Nephrology, Mahatma Gandhi Medical College and Research Institute, SBV University, Puducherry, India

Correspondence Address:
Dr. Vijesh Anand
Senior Resident, Department of Cardiology, Mahatma Gandhi Medical College and Research Institute, SBV University, Puducherry
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JICC.JICC_26_19

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Aims: This study was aimed to assess the left ventricular filling pressure (LVFP) and its relationship with severity of chronic kidney disease (CKD). Methods: One hundred CKD patients were subjected to standard echocardiography and the new modality of tissue Doppler imaging. The LVFP is calculated with E/e' ratio (early diastolic mitral inflow velocity – E to early diastolic mitral annulus velocity – e'). All these patients were divided into five subgroups depending on their estimated glomerular filtration rate (eGFR: ml/min/body surface area). Results: The analysis of echocardiographic parameters (E and e') showed that in CKD patients, the stage of renal failure was associated with the significant increase in LVFP with P < 0.001. There was a significant correlation between LVFP and eGFR with r = −0.467 and P < 0.001. Conclusion: These data suggest that LVFP starts to raise early in the case of CKD. The increase in LVFP is directly proportional to the severity of renal failure.


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